Purpose
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Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ibudilast is currently in development in the U.S. (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.
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Characteristics
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Tradename: KC-404, MN-166 Target: PDE inhibitor Receptor: PDE
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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99?%
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Formula
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C14H18N2O
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Solubility
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DMSO:28 mg/ml,100 mM in ethanol
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