產(chǎn)品詳情

  • 產(chǎn)品名稱：MemantineHCl

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
MemantineHCl
詳情介紹：
Purpose Memantine is an uncompetitive NMDA receptor antagonist. When using HEK293 cells express recombinant rat NMDA receptors, memantine shows inhibition of L-glutamate-mediated response with a dose- and voltage-dependent manner. Memantine also has a rapid unblocking kinetics. Memantine is used clinically in spasticity, Parkinson's disease and Alzheimer's disease. Memantine is found to attenuate the deleterious action of Aβ in the in vitro numerous studies. It is probably due to the decreased tau phosphorylation caused by memantine
Characteristics Tradename: NAMENDA
Source of Compound: synthetic
Target: AMPAR inhibitor, NMDAR inhibitor
Receptor: AMPA receptor, Kainate receptor, NMDA receptor
Status: USAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 95?%
Formula C12H22ClN
Solubility Soluble in DMSO > 13 mM
Molecular Weight 215.76 g/mol
CAS-No 41100-52-1
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months