產(chǎn)品詳情
  • 產(chǎn)品名稱(chēng):Chloralhydrate

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  • 產(chǎn)品廠商:TargetMol
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簡(jiǎn)單介紹:
Chloralhydrate
詳情介紹:
Purpose Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties. Chloral hydrate is converted to the active compound trichloroethanol by hepatic alcohol dehydrogenase. The agent interacts with various neurotransmitter-operated ion channels, thereby enhancing gamma-aminobutyric acid (GABA)-A receptor mediated chloride currents and inhibiting amino acid receptor-activated ion currents. In addition, chloral hydrate enhances the agonistic effects of glycine receptors, inhibits AMPA-induced calcium influx in cortical neurons, and facilitates 5-HT 3 receptor-mediated currents in ganglionic neurons. Overall, this results in a depressive effect on the central nervous system.
Characteristics Tradename: Aquachloral, Novo-Chlorhydrate, Somnos, Noctec, Somnote
Source of Compound: synthetic
Target: GABAR
Receptor: GABA receptor
Status: USAN, JAN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C2H3Cl3O2
Solubility 10 mM in DMSO
Molecular Weight 165.40 g/mol
CAS-No 302-17-0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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