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  • 產(chǎn)品名稱：Methotrexate

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Methotrexate
詳情介紹：
Purpose Methotrexate, a folate antagonist, is a potent anti-inflammatory agent when used weekly in low concentrations, the anti-phlogistic action of which is due to increased adenosine release at inflamed sites. Studies have demonstrated that methotrexate polyglutamates are active inhibitors of several enzymatic reactions, including dihydrofolate reductase.
Characteristics Tradename: RHEUMATREX
Source of Compound: synthetic, amethopterin, CL-14377
Target: DHFR inhibitor
Receptor: DHFR
Status: USP, INN, BAN, JAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?%
Formula C20H22N8O5.2H2O
Molecular Weight 454.44 g/mol
CAS-No 59-05-2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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image for Methotrexate (ABIN4874016) Methotrexate