Purpose
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A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
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Characteristics
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Tradename: HIVID Source of Compound: synthetic, RO-24-2027 Target: Reverse Transcriptase inhibitor Receptor: Reverse Transcriptase Status: USP, INN, BAN
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98?%
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Formula
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C9H13N3O3
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Solubility
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Very soluble in water
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