產(chǎn)品詳情

  • 產(chǎn)品名稱：CFTRInhibitor-172

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  • 產(chǎn)品廠商：Biovision
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簡單介紹：
CFTRInhibitor-172
詳情介紹：
Purpose A potent, CFTR chloride channel blocker
Characteristics A potent, reversible, selective, CFTR chloride channel blocker. Inhibits CFTR short-circuit current in < 2 minutes in a voltage-independent manner (Ki = ~ 300 nM). At concentrations fully inhibiting CFTR, CFTR(inh)-172 does not block increase of cellular cAMP or inhibit non-CFTR Cl(-) channels, multidrug resistance protein-1 (MDR-1), ATP-sensitive K(?) channels, or a series of other transporters.
Purity ≥ 98?% by HPLC
Chemical Name 4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid; CFTR(inh)-172
Formula C??H??F?NO?S?
Permeability Not-permeable
Solubility DMSO (> 10 mg/mL)
Molecular Weight 409.4 g/mol
CAS-No 307510-92-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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