Background
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IgG constitutes about 70 % of all immunoglobulins and are responsible for neutralizing toxins. Reduced IgG levels may be associated with IgA myeloma, nephrosis or a congenital deficiency. Increased levels of IgG antibodies are seen in infections, autoimmune disease and certain allergic responses. High levels of a monoclonal IgG may be due to myeloma.
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