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  • 產(chǎn)品名稱:HumanIgMIsotypeControl

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  • 產(chǎn)品廠商:BioLeaf
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HumanIgMIsotypeControl
詳情介紹:
Isotype IgM
Characteristics Purified Human IgM protein (Fab mu)
Source: Human serum
Alternative Names: Immunoglobulin M protein (Human) (Fab mu)
Physical state: Clear, colorless liquid
Purification Purified
Background Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. It is the primary antibody against A and B antigens on red blood cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to antigen. The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. These domains shape the paratope - the antigen- - at the amino terminal end of the monomer. The two variable domains bind the epitope on their specific antigens.
Synonyms: Immunoglobulin M protein (Human) (Fab mu).
Research Area Secondary Antibodies, Immunology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer 0.02 M K2 O4, pH 7.2, with 0.12 NaCl, and 0.01 % NaN3.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Storage 4 °C
Storage Comment Store at 4 °C.