產(chǎn)品詳情
  • 產(chǎn)品名稱:HumanIgG3IsotypeControl

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  • 產(chǎn)品廠商:BioLeaf
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簡單介紹:
HumanIgG3IsotypeControl
詳情介紹:
Isotype IgG3
Characteristics Purified nativeHuman IgG3 protein
Source: Human normal plasma
Alternative Names: Human IgG3 Whole Molecule, Immunoglobulin G3 Protein
Purification Purified
Purity > 95 % pure
Background Like IgG1, IgG3 activates complement and has an affinity for fc receptors, thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.
Synonyms: Human IgG3 Whole Molecule, Immunoglobulin G3 Protein.
Molecular Weight 170 kDa
Research Area Secondary Antibodies, Immunology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer 20 mM phosphate, pH 7.4, with 150 M NaCl and 0.05 % NaN3.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze.
Because IgG3 antibodies tend to aggregate after freezing and thawing, freezing of these antibodies is not recommended.
Storage 4 °C
Storage Comment Store at 4 °C.